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Objective In utero exposure of the fetus to Ro/La autoantibodies may lead to congenital heart block (CHB). In the mother, these autoantibodies are associated with activation of the type I interferon ...
Anti-Ro/SSA antibodies, prevalent autoantibodies in connective tissue diseases, have well-established roles in fetal arrhythmias but their significance in adult arrhythmias remains underrecognized.
Assessment of fluorinated steroids to avert progression and mortality in anti-SSA/Ro-associated cardiac injury limited to the fetal conduction system Peter M Izmirly 1, ...
Playing music has long been a way for expectant parents to connect with their children in the womb, but a group of researchers has found evidence it can calm fetal heart rates, potentially ...
A Sjogren’s antibody test uses a blood sample to measure key autoantibody levels. However, those with Sjögren disease don't always have these autoantibodies.
Antibodies that bind to a previously untargeted portion of the malaria parasite could lead to new monoclonal antibody treatments and vaccines for malaria.
Reducing fetal exposure to maternal anti-SSA/Ro autoantibodies by selectively targeting IgG recycling via inhibiting neonatal Fc receptors, thereby accelerating the destruction of IgG as well as ...
Fetal autoimmune atrioventricular block (AVB) is a rare but potentially life-threatening condition. It results from the passage of maternal anti-SSA/Ro or Anti SSB/La auto-antibodies into the fetal ...
Anti-Ro/SSA antibodies predicted which patients were at most risk for ILD but not ILD progression or overall disease progression and death.
Abstract Introduction: Fetal complete AV block (CAVB), complicates 2% of anti-Ro antibody positive pregnancies and carries substantial perinatal morbidity and mortality. Anti-inflammatory treatment of ...
Nov 22, 2023 Share this article: The following is a summary of “Prospective Evaluation of High Titer Autoantibodies and Fetal Home Monitoring in the Detection of Atrioventricular Block Among ...
Women with anti-SSA/Ro antibodies were stratified into high and low anti-52kD and/or 60kD SSA/Ro titers. Fetal heart rate monitoring (FHRM) was performed three times a day in the high-risk group, and ...