BriaPro plans on developing anti-B7-H3 antibodies for multiple cancer indications and plans to incorporate them into its Bria-TILsRx™ platform—a proprietary antibody platform designed to ...

Novartis has finally given up on iscalimab after deciding that the anti-CD40 antibody is not worth pursuing in Sjögren’s syndrome. On a fourth-quarter earnings call with the media this morning ...

How do you see anti–CD-38 monoclonal antibodies changing the standard of care in multiple myeloma? Anti–CD-38 monoclonal antibodies like daratumumab and isatuximab have really transformed the ...

More information: Ryota Sada et al, Newly developed humanized anti‐CKAP4 antibody suppresses pancreatic cancer growth by inhibiting DKK1‐CKAP4 signaling, Cancer Science (2024). DOI: 10.1111 ...

VIENNA — Anti-Ro/SSA antibodies may help predict which patients with systemic sclerosis (SSc) are at a greater risk for interstitial lung disease (ILD) and may serve as a biomarker to guide ...

Please provide your email address to receive an email when new articles are posted on . SAN DIEGO — Pregnant patients with very low anti-Ro antibody titers of less than 1,000 units per mL have ...

SAN DIEGO, California — Pregnant women with anti-SSA/Ro autoantibodies at titer levels of less than 1000 ELISA units per mL are at minimal to no risk for fetal atrioventricular (AV) block and ...

In the trial, called Surveillance To Prevent AV Block Likely to Occur Quickly (STOP BLOQ), the incidence of AVB increased with higher levels of anti-Ro/SSA antibodies, reaching 7.7% for those in ...

Some individuals with anti-Ro/SSA antibodies (anti–Sjögren's-syndrome–related antigen A autoantibodies, also called anti-Ro antibodies) have autoimmune diseases such as lupus or Sjögren's ...

Anti-Ro antibodies are autoantibodies that react with two proteins, Ro52 and Ro60, inside cells. The antibodies are associated with many autoimmune diseases, including lupus, Sjögren's ...

Atezolizumab 31 0–54.1 29.6% (639) 4.3–27.5 Durvalumab 14 0–74 0% (416) 0–0.9 Abbreviations: ADA, anti-drug antibody; nAb, neutralising antibody; NR, not reported. This is an ASCO Meeting Abstract ...

Higher affinity is the primary goal in the production of therapeutic monoclonal antibodies that directly bind to foreign proteins on pathogens or abnormal proteins on cancer cells. A new study ...