C2H2 zinc finger proteins are the largest group of ... controlling the length of mRNA through mechanisms called cleavage and polyadenylation and altering mRNA after transcription via enzymes ...

In summary, our study uncovers somatic mutation within the zinc finger domains as a novel mechanism alternative to chromosome deletion in the inactivation of tumor suppressor function of ZBTB7A.

Zinc fingers might be the answer to that seemingly insurmountable challenge. Historically, however, viruses have been the only viable mechanism for faulty gene repair (let's call it gene therapy).

The recent development of engineered zinc finger nucleases (ZFNs ... process to target editing of the genome despite the natural mechanisms developed by mammalian genomes to prevent genome ...

An artificial intelligence program may enable the first simple production of customizable proteins called zinc fingers to treat diseases by turning genes on and off. The researchers at NYU ...

The guide sequence found within CRISPR RNAs typically correlates to bacteriophage sequences, constituting the mechanism for CRISPR ... of the designed zinc-finger domain points the ZFN to a ...

These proteins are called Zinc Finger proteins, and can recognize and bind to specific DNA sequences. This enables the regulation of those genes to which they are attached. A study conducted by ...

Previous generations of gene-editing tools are still very much in play — particularly zinc finger nucleases, TALEN, and meganucleases. And there’s a bit of a misconception that the prior ...