Tda1 protein kinase, activated by Snf1 and yeast GSK3-β, fine-tunes metabolism through the phosphorylation of Hxk2, which is implicated in yeast glucose repression. Tda1 is activated by both Snf1 and ...

Y2H is a genetic method that relies on the modular architecture of transcriptional activators to identify protein-protein interactions in the yeast nucleus. At first, researchers used Y2H mainly to ...

Fred Chang, PhD, MD, uses a Confocal microscope to view a yeast cell with an oversized nucleus. Photo by Barbara Ries Using fission yeast as a model organism, his lab explores fundamental aspects of ...

By anchoring transcription factors (and the genes they regulate) to nuclear pore proteins, Exportin-1 helps reposition genes to the edge of the nucleus. This relocation ... Arts & Sciences has mainly ...