“Our idea is that instead of modifying an existing chromosome, we design it from the ground up,” explained Prof Harris. “We’re rethinking what plants can do for us. This synthetic chromosome could one ...

A world-first effort to build an artificial chromosome entirely from scratch in plants has received more than $12 million in ...

Two groups involving researchers from the University of Cambridge’s Department of Plant Sciences are among nine teams to have ...

A new project, co-led by Dr Joshua James and Professor Patrick Cai of the Manchester Institute of Biotechnology at The ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During mitosis, centromeres ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

Biochemical reconstitution and laser trapping show that centromeric DNA sequences are important for the transmission of microtubule-based forces to chromosomes.

Final synthetic yeast chromosome unlocks new era in biotechnology. ScienceDaily . Retrieved June 3, 2025 from www.sciencedaily.com / releases / 2025 / 01 / 250122125522.htm ...

The research team used specialised gene editing tools to identify and fix problems in the synthetic chromosome affecting how well the yeast could reproduce and grow under challenging conditions.

It was a “watershed” moment in an 18-year-long project to design alternate versions of every yeast chromosome. Despite having seven and a half synthetic chromosomes, the cells reproduced and thrived.

NEW YORK, Nov. 8, 2023 /PRNewswire/ -- A team led by researchers at NYU Langone Health has built nine new synthetic yeast chromosomes, swapping out a key organism's genetic material for ...