Each cell of the human body contains two meters of DNA. The whole secret lies in the intricate three-dimensional arrangement ...

This study presents an important discovery regarding the diversity and evolution of gall-forming microbial effectors. Supported by convincing computational structural predictions and analyses, the ...

This important manuscript proposes a new strategy for the identification of new mechanisms of drug resistance based on SAturated Transposon Analysis in Yeast (SATAY), a powerful transposon sequencing ...

Scientists uncover how the nucleolus, a tiny structure within cells, may control aging and lifespan, opening new ...

A sophisticated molecular machine, the spliceosome, ensures the accurate assembly of genetic information from the genome into ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...

Dr. Irmgard Sinning used the fission yeast Schizosaccharomyces pombe, a model organism frequently used in cell biology ... "The largely stable structure of the spliceosome center enabled us ...

A vaginal yeast infection is caused by an overgrowth of yeast (a type of fungus) in the body. People with diabetes are more prone to getting these infections because their blood sugar levels are often ...

Specificity also entails recognition of and selective activity towards particular ubiquitin chain types, at least eight of which are now known to coexist in yeast and mammalian cells. DUBs might ...

Deshaies and Ferrell (2001) have indicated that the normal concentration of Sic1 in budding yeast cells may be around 1 μM ... due to the purification step, the structure of the majority of the Fba1 ...

This doesn't mean we can start growing completely artificial yeast from scratch, but it does mean living yeast cells can potentially be entirely recoded – though lots more work is required to get this ...