Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

The work provides a comparative evaluation of the characteristics of various large DNA fragment assembly strategies used in different host cells, focusing on their limitations, time requirements, and ...

For example, the evolution of much smaller but fully functional centromeres (involved in controlling cell division) in bonobos may offer ideas for engineering streamlined artificial chromosomes to ...

Ghosh. “It attaches itself to the host cell’s chromosomes, ensuring it gets separated along with them during division.” The research outlines how yeast, which reproduces by budding ...

Deep within the cells of mice, a genetic arms race is unfolding between X and Y chromosome genes, battling for dominance in sperm. Researchers have now discovered how these gene families compete by ...

This competition, or arms race, is typically hard to observe–except when the genes in question live on the X and Y chromosomes, which determine ... Sly gene families from mouse and putting them into ...

Before division, the yeast cell duplicates its chromosomes, wherein both the mother and daughter cells receive a complete set of genetic material. Similarly, the 2-micron plasmid also duplicates and ...

Synthetic chromosomes can be neatly organised ... Then, one chunk at a time, Goold replaced the genome of normal lab yeast with the artificial DNA by culturing a concoction of yeast, lithium ...