Electroacupuncture (EA) has both anti-inflammatory and cardio-protective effects. Activation of calpain pathway is involved in several myocardiopathy. In sepsis, the role of calpain-2-regulated STAT3 ...

[26–28] They found calpain 3 was not detected by western blotting, which is probably due to its degradation by nonsense-mediated mRNA decay. Three patients harbored two null alleles, and were ...

Neurons are cells in the body that are responsible for transmitting electrical signals through the nervous system. Different types of neurons affect the ability to move, which begins as an impulse, or ...

Mass Effect 5 is officially in the works from BioWare. First revealed back in 2020 with a brief teaser that sparked excitement among fans of the beloved sci-fi RPG, it's been some time since we've ...

“The targeted nano-formulation inhibited the mitochondrial translocation of calpain, thereby protecting neurons from rotenone-induced mitochondrial damage,” the researchers said. Furthermore, in a ...

As Mass Effect 2 celebrates its 15th anniversary, we look into why the new game is taking so long and whether it will ever be out. BioWare’s history is built on a wealth of critically-acclaimed ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--$AMLX--Amylyx Pharmaceuticals, Inc. (NASDAQ: AMLX) (“Amylyx” or the “Company”) today announced that the U.S. Food and Drug ...

Most people grow a dozen molars, but many have fewer after the removal of their wisdom teeth, which are a type of molar. These start to appear when babies are about 13 to 19 months old ...

Calpain is a conserved cysteine protease readily expressed in several mammalian tissues, which is usually activated by Ca 2+ and with maximum activity at neutral pH. The activity of calpain is tightly ...