Researchers from the University of Colorado Cancer Center have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. Peter Dempsey, Ph.D., professor ...

Most of the time, the intestinal immune system can recognize friend from foe, tolerating myriad foods while destroying disease-causing invaders. But for approximately 30 million Americans with food ...

Intestinal stem cells are multipotent adult stem cells, which in mammals reside in the base of the crypts of the adult intestine. Intestinal stem cells continuously self-renew by dividing and ...

In our laboratory, we delve into the intricate mechanisms employed by intestinal cells to secure the vital nutrients and metabolic resources essential for preserving intestinal stem cell fate and ...

Compare that with the cells that line your small intestine, which have dozens of tiny, fingerlike projections to maximize the surface area across which nutrients can pass. But how, exactly ...

Vitamin D deficiency is highly prevalent in the US and around the world. Roughly 15.4% of children and adolescents in the US were vitamin D deficient in 2017. While vitamin D deficiency has slightly ...

"The intestine has an enormous ability to regenerate itself after injury, and it does this through a model of dedifferentiation," Dempsey explains. "The cells dedifferentiate back into a type of ...

"The intestine has an enormous ability to regenerate itself after injury, and it does this through a model of dedifferentiation," Dempsey explains. "The cells dedifferentiate back into a type of ...