Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies.

Researchers expect LICONN technology will be broadly useful to enable high-resolution tissue analysis in other organs and ...

Light-microscopy based dense connectomic reconstruction of mammalian brain tissue. Nature. DOI: 10.1038/s41586-025-08985-1 High-Resolution Optical Imaging for Biology research group at ISTA Genetic ...

LICONN is the first technology beyond electron ... of the structural reconstruction.” What stands out is that the image acquisition is done on a standard off-the-shelf microscope, which is ...

The emergence of cryo-electron microscopy ... dimensional reconstruction from projections is the same in cryo-EM and in medical tomography 2. A major issue for cryo-EM is image contrast.