Tobacco-based products, including e-cigarettes, have gained popularity as perceived safer alternatives to traditional smoking despite their addictive nature. However, emerging evidence shows that ...

Molecular glues are monovalent small molecules that enhance or create protein-protein interaction, leading to the ubiquitination and degradation of target proteins when an E3 ubiquitin ligase ...

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While inflammasome activation is a well-characterized pathway, the non-inflammasome functions of these ... The CARD domain of ASC can then interact with the CARD domain of pro-caspase-1 to facilitate ...

Department of Biochemistry and Biophysics, College of Agriculture and Life Sciences, Texas A&M University, College Station, Texas 77843, United States ...

A cis-regulatory analysis identified 1,327 essential interactions ... of pathways such as oxidative phosphorylation, which is essential for ATP production and may be compromised by oxidative stress.