No writing assistance was utilized in the production of this manuscript. Tyrosine kinase inhibitors (TKIs) are used for the targeted treatment of cancer. TKIs produce a range of serious adverse ...

Rusfertide (PTG-300) treatment in phlebotomy-dependent polycythemia vera patients. Overall survival by IDH2 mutant allele (R140 or R172) in patients with late-stage mutant-IDH2 relapsed or refractory ...

Based on a phosphoryl transfer mechanism involving a dissociative transition state, a potent and selective bisubstrate inhibitor for the insulin receptor tyrosine kinase was synthesized by linking ...

SU11657 (SUGEN) is a selective multitargeted tyrosine kinase inhibitor with antitumor and antiangiogenic activity exerted by targeting PDGF receptors (PDGFR), VEGF receptors (VEGFR), stem cell ...

Cartoons Monday's political cartoons include Elon Musk's next project, the Democratic party's efforts to win more male votes, and Donald Trump's taco order. Cartoons Sunday's political cartoons ...

Keep in mind that we don’t get to pick which quests we go on, and most of them are pretty Jesus-y. We have been so touched by the flood of D.M.s, the comments posted on Nextdoor, and the notes ...

Editorial cartoonists leapt upon the revelation that former President Joe Biden has advanced prostate cancer, followed by publication of a new book revealing the extent of White House efforts to ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

“This book is banned, but the internet is fair game.” ...

Don’t take medical advice from RFK Jr. Review-Journal editorial cartoonist Michael Ramirez is a two-time winner of the Pulitzer Prize and a four-time winner of the Sigma Delta Chi Award.