Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which ... The focus is on early tumor growth prior to angiogenesis and the ...

Research has shed light on how a new type of antibody treatment reactivates patients' immune cells to fight ovarian cancer.

Mar. 13, 2025 — A study shows that high-grade glioma tumor cells harboring DNA alterations in the gene PDGFRA responded to the drug avapritinib, which is already approved by the United States ...

In contrast to current nonspecific immunosuppressive agents, the emergence of immunomodulatory drugs provides the possibility of interfering with specific pathogenic pathways. Novel targeted ...

There has been little innovation in immunosuppression therapy for organ transplant patients over the past 30 years. The standard of care immunosuppressive drugs used post-transplant have been ...

Salmonella infections, prevalent globally, correlate with increased risk of cancer, particularly gallbladder and colon cancers. In this Comment, Stévenin and Neefjes highlight the need for ...

Kathryn L. Grant, Pharm.D., Assistant Professor College of Pharmacy, Craig D. Schneider, M.D., Fellow, Program in Integrative Medicine College of Medicine, University ...

Apr. 9, 2025 — A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, according to new ...