VEGF is likely to continue to be considered a central factor in the regulation of angiogenesis, but by no means limited to cancer 104,105. It is also possible that VEGF inhibition will have an ...

Two, that it recruited the vessels by sending out some factor, which we called TAF, tumor angiogenesis factor, because we didn't know what it was that was diffusible. (Diffusion means like if you ...

or perhaps by the time the tumor has broken through the basement membrane (as pictured above), angiogenesis takes place. Angiogenesis is the recruitment of blood vessels from the network of ...

A new review in Genes and Diseases explores the central role of MYC, a master regulatory protein, in the development and progression of cancer, spotlighting its potential as a multidimensional ...

Lu says the new study demonstrates that, instead of inhibiting dysfunctional tumor angiogenesis by anti-VEGF ... looked at vascular endothelial growth factor (VEGF), a signaling protein that ...

announced it was aborting its Phase III colorectal cancer clinical trial of SU5416, as no clinical benefit was found. SU5416 is a small-molecule angiogenesis inhibitor that blocks the action of ...

Metastatic cancer, the primary cause of cancer mortality, frequently exhibits heightened dependence on certain transcription factors (TFs), which serve as master regulators of oncogenic signaling yet ...

Prostate-specific membrane antigen (PSMA) gene expression predicts angiogenesis and response to tyrosine kinase inhibitors (TKIs) in patients with metastatic clear cell renal cell carcinoma (RCC), ...