Early research shows that editing expanding trinucleotide repeats halts the lengthening process that causes neurological ...

Broad Institute researchers have developed a way to edit the genetic sequences at the root of Huntington's disease and ...

behavioural abnormalities and progressive disease course proves negative to the genetic testing for HD causative mutations, that is, IT15 gene trinucleotide-repeat expansion. The differential ...

CRISPR–Cas base editing of trinucleotide repeats shows promise in reducing somatic repeat expansions in Huntington’s disease and Friedreich’s ataxia, offering a potential new therapeutic ...