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DNA trinucleotide repeat expansions are known to be associated with several hereditary neurodegenerative disorders, including Huntington disease, Fragile X syndrome and spinocerebellar ataxia.
Hosted on MSN14d
Brain Changes Emerge Decades Before Huntington's DiagnosisHuntington's is an autosomal dominant genetic disorder caused by extended CAG trinucleotide repeats in the huntingtin (HTT) gene. The sequence tends to expand continually in a process known as ...
Hosted on MSN23d
Beta-Blockers Tied to Delayed Huntington's Disease ProgressionHuntington's is an autosomal dominant genetic disorder caused by extended cytosine-adenine-guanine (CAG) trinucleotide repeats in the huntingtin (HTT) gene. The number of CAG repeats in the HTT ...
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