DNA trinucleotide repeat expansions are known to be associated with several hereditary neurodegenerative disorders, including Huntington disease, Fragile X syndrome and spinocerebellar ataxia.

Huntington's is an autosomal dominant genetic disorder caused by extended cytosine-adenine-guanine (CAG) trinucleotide repeats in the huntingtin (HTT) gene. The number of CAG repeats in the HTT ...