The targeting of transport vesicles to the correct membrane destination involves a much larger set of proteins than anticipated and several layers of protein–protein interactions. The process of ...

Cells intake substances from the outside world by encapsulating them in vesicles called endosomes, which are subsequently ...

Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through blood vessels and bodily fluids: special proteins that keep their ...

The Golgi apparatus transports and modifies proteins in eukaryotic cells. How have scientists studied dynamic protein movements through the Golgi? One of the principal observations by Rothman's ...

Our research group studies the mechanisms of protein trafficking and quality control at the endoplasmic reticulum (ER) in mammalian cells. A major focus of research is on the COPII protein machinery ...

During the first 72 hours in particular, extracellular vesicles—nanoparticles enclosed in cell membranes—play a significant role in the embryonic development of zebrafish. This is the result ...