A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the ...

A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the ...

APP 695 SWE mice expressing transgenic human APP with the two-point (Lys 670 →Asn, Met 671 →Leu) 'Swedish' mutation show age-dependent impairments in several histopathological features ...

Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...

Here we created an HBV transgenic severe combined immunodeficiency (SCID) mouse that consistently supports HBV gene expression and replication. After adoptive transfer of syngeneic, unprimed ...

The International Day of Women and Girls in Science is celebrated on February 11th each year. It's a day to recognise the ...

The genes that build the cartilage of fish gills were repurposed to build the cartilage in mammals’ outer ears ...

2002). In addition to motor neuron loss, these mice also lose superficial cortical neurons. The number of NeuN-positive cortical neurons was comparable to wild-type at 2 months of age, but transgenic ...

Antibody drugs have reshaped how we treat diseases. By harnessing the immune system to destroy tumours or temper excessive inflammation in autoimmune disorders, these therapeutics have become ...

The study's findings are crucial in the rapidly emerging field of developing disease-modifying therapies that target microglia.

Microglia, the brain’s immune cells, play vital roles in clearing toxins and maintaining neuronal health but can also contribute to neurodegenerative diseases if overactive.