Researchers engineered a new gene system in the parasite A. deanei using a bacteriophage enzyme and novel drug markers. This ...

Sensing environmental temperature is crucial for the development and survival of animals. Insects such as fruit flies have ...

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely ...

Researchers discovered that two neighboring genes, old and zao, regulate antiviral responses and symptom expression in the ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

Meanwhile, CDK7’s other role—of kick-starting enzymes that nudge cells to divide and multiply—is also blocked by the inhibitor they tested, but this occurs more slowly and is not dependent on the core ...

This halt then resolves and the enzyme can move ahead again, churning out RNA. "In early days, people thought that once RNA polymerase begins transcription, it will finish it without any problems ...

For example, where an abundance of enzymes induced by dysregulated genetic transcription is causing the cancer cell to proliferate more quickly, drugs can be used to target and thus regulate the ...

where they activated gene transcription. "This work provides new tools, which overcome long-standing limitations in studying the functions of individual PKC enzymes and provides greater ...

These enzymes catalyze chemical reactions that modify the structure or sequence of DNA, including replication, repair, recombination, and transcription. In this article, we will explore the importance ...

Now, scientists led by postdoctoral researcher Linda Forero-Quintero have, for the first time, observed early RNA transcription dynamics by recording where, when and how RNA polymerase enzymes ...