A study by researchers at Fred Hutch Cancer Center published in Nature revises the standard story about transcription factors ...

Cancer drugs that inhibit CDK7 rapidly shut down pathways responsible for cell proliferation within minutes. For organs to develop, grow, and regenerate, cells must divide and multiply, a process ...

We present a transcription-based hybrid probe, referred to as Hybprobe, and a CRISPR/Cas12a signal amplifier for the rapid, sensitive, and low-cost detection of RNase H activity. In this method, the ...

This standard oscillator refers to the transcriptional translation feedback loop (TTFL). Two transcription factors named circadian locomotor output cycles kaput (CLOCK) and brain and muscle ARNT-like ...

oxysporum, characterized by a negative feedback loop involving the transcription factors FoWC1, FoWC2, and the core clock protein FoFRQ. Among multiple Fofrq genes contributing to the circadian ...

Reporting in Science Translational Medicine, the team highlighted an enzyme named GPT1, which stands for glutamic-pyruvic transaminase 1. Colorectal cancer, the researchers asserted, is ...

Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States Center for Metals in Biocatalysis, University of Minnesota, Minneapolis, Minnesota 55455, United States ...