New research offers unprecedented insight into how an enigmatic enzyme, known as CDK7, drives the cell cycle and cell proliferation.

Researchers harness the power of the world’s most advanced supercomputers to simulate the inner workings of cellular ...

In other experiments, this same set of transcription factors was found ... Meanwhile, CDK7’s other role—of kick-starting enzymes that nudge cells to divide and multiply—is also blocked ...

For organs to develop, grow and regenerate, cells must proliferate. But when that process goes awry, leading to uncontrolled cell growth, cancer can emerge.

Kanazawa University, report in Nature Communications how the targeted suppression of lysosome function may lead to brain cancer therapy. Glioblastoma is a type of brain cancer with a ...

The field of synthetic biology is revolutionizing biomedicine, with applications in CAR-T cell therapy and biosensor-based ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...