The data convincingly show that the transcription factor Sp1 regulates ephrin-mediated axon guidance in the spinal cord. Although the authors show that Sp1 and its co-activators p300 and CBP are ...

Neuroscientists have produced the largest wiring diagram and functional map of a mammalian brain to date using tissue from a ...

From a tiny sample of tissue no larger than a grain of sand, scientists have come within reach of a goal once thought unattainable: building a complete functional wiring diagram of a portion of the ...

Researchers say they have mapped more than 200,000 cells in a cubic millimeter of brain tissue and have traced how they're all connected.

Transcription is the process by which an RNA polymerase synthesizes ribonucleic acid (RNA) using deoxyribonucleic acid (DNA) as a template. CEBPA is frequently mutated in acute myeloid leukemia ...

(NEXSTAR) – New cases of a dangerous, drug-resistant fungus have been identified in at least two states’ hospital systems. Candida auris, also called C. auris, was first identified in the U.S ...

CD47-amyloid-β-CD74 signaling is a key driver of adaptive immunosuppression in sepsis, suppressing B cells and impairing ...

This manuscript demonstrates that Oct4 overexpression synergizes with Notch inhibition (Rbpj knockout) to promote the conversion of adult murine Müller glia (MG) into bipolar cells. These findings are ...

It may be hard to imagine, but navigating grief for “too long” used to be labeled as a mental illness. How we handle grief is personal — some argue, a part of someone's personality ...

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, but effective treatments are lacking. Cardiac lymphatics play a crucial role in ...

Liver TET1 was found to promote metabolic dysfunction-associated steatotic liver disease (MASLD) by regulating CD36 expression, suggesting TET1 as a therapeutic target for MASLD treatment. TET1 ...