including T cell lymphocytes which are matured in the thymus. The fundamental discovery of the key role that the thymus plays in the development of our immune system underpins our understanding of ...

UbiVac’s DPV-001 induces Development of 1st in-patient generated TCR to Non-Small Cell Lung Cancer’s “Dark Matter” – Targets cancer without apparent toxicity UbiVac is thrilled to announce the first ...

How your immune system really ages — research shows aging brings adaptation not decline and reveals ways to maintain immune ...

[36] Gender-specific patterns in the development of autoimmune diseases ... the combined effects of the reduction in naive T cells (produced by thymus involution) in concert with an activation ...

A phase I study of a next-generation CAR T cell therapy showed a 52 percent complete remission rate for patients with relapsed/refractory lymphoma.

A next-generation "armored" CAR T cell therapy showed promising results in a small study of patients whose B-cell lymphomas continued to resist multiple rounds of other cancer treatments, including ...

WEHI scientists have uncovered a promising new way to enhance the effectiveness of vaccines by tapping into the potential of a specific type of immune cell, opening the door to long-lasting vaccines ...

Mechanism whereby T cell plasticity, a process originating in the gut and aided by gut microbiota, promotes autoimmunity at gut-distal sites.

A key enzyme and its molecular pathway are critical to keeping certain immune cells active and away from "exhaustion," ...

Author for correspondence Tel.: +44 191 222 5462 steven.o'[email protected] T cells develop in the thymus, where they undergo positive and negative selection to produce a nonself-binding T ...