At its third attempt, Mesoblast has secured FDA approval for Ryoncil as a treatment for children with graft-versus-host disease, the first-ever approval for a mesenchymal stromal cell (MSC ...

Here, they are captured by the APCs, which then cause apoptosis among the antigen-specific T cells or differentiation in the suppressor T cells, which produce suppressive TGF-b. A breach in the ...

Methods: To determine the potential involvement of PXR in the regulation of steroidogenesis, experiments were performed on a wild type (MLTC-1WT) and a Pxr knock-down (MLTC-1PxrKD) mouse Leydig cell ...