Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

Results Patients with IMDs were stratified into two clusters based on their immunophenotypes. Cluster 1 was enriched with differentiated B cells, including unswitched memory B cells (USM B), switched ...

Isolated B cells and Tfh cells were cocultured as previously described with minor modifications (23, 24). 3×10^5/well B cells were cultured with or without 1.5×10^5/well Tfh cells in the presence of ...

Systemic lupus erythematosus (SLE) is characterised by numerous abnormalities in B lineage cells, including increased CD27++ plasmablasts/plasma cells, atypical CD27-IgD- B cells with increased CD95, ...

Immune cell feedback drives thymus's complex architecture, new model reveals by Ludwig Maximilian University of Munich edited by Lisa Lock, reviewed by Robert Egan Editors' notes ...

The B-1 cell population derives from splanchno-pleural area and fetal liver and differentiates into CD5 + CD19 + CD23 – CD43 + IgM high IgD low B-1a and CD5 – CD19 + CD23 – CD43 + IgM high IgD low ...