Given that indirect presentation of murine antigens on human APCs is sufficient to drive disease 1 and is required for survival of transferred human T cells 30, we conclude that incomplete negative ...

After cross-referencing these datasets and others to identify different thymic cell types based on specific gene signatures, Kousa and team had rich information about a dizzying array of cell ...

Interestingly, these clusters developed into thymic tissue with no function and only got worse with age. More specifically, as the organ aged, the stem cells became less stable and loss their ability ...

The organoids, derived from mouse thymus tissue, specifically model thymic epithelial cells (TECs). These cells are responsible for training the T cells of the immune system to properly respond to ...

Researchers from the Organoid group have developed a new organoid model that can be used to study the thymus. The organoids, derived from mouse thymus tissue, specifically model thymic epithelial ...

Learn about the purpose of a thymectomy and what happens before, during, and after the procedure. This article also discusses recovery, risks, and more.

The thymus is not only responsible for supporting normal immune cell development, but may also potentially restore immune system function as people age. More than 10,000 new patients are diagnosed ...

The thymus is a critical organ in the immune system that regulates and develops T cells, which are essential for fighting infection and disease, along with mounting effective responses to vaccines.

The thymus gradually wastes away and gets replaced by fat. “It progressively becomes something that looks like more of a fatty blob,” says hematologist-oncologist David Scadden of ...

Resolve will begin offering FFPE tissue capabilities as part of its Meridian service program and will add the feature to its commercial Molecular Cartography systems later this year.