Thymic epithelial cells provide the microenvironment required for the expansion of T cells in the thymus, but their exact function is not well understood. Here, the authors report that thymic ...

The thymus is a crucial training ground for T-cells, the body's "white knights," where they learn to battle the various ...

Thymic epithelial cells are indispensable in the development of T cells but little is known about precursor-progeny relationships between distinct thymic epithelial lineages. In June 17 Advanced ...

The thymus functions as the primary lymphoid organ responsible for the generation of T cells and plays a crucial role in preventing autoimmune reactions by eliminating autoreactive cells before ...

The thymus provides the essential microenvironment for T-cell development and maturation. Thymic epithelial cells (TECs), which are composed of thymic cortical epithelial cells (cTECs) and thymic ...

However, these findings, published today in Developmental Cell, show for the first time the presence of self-renewing stem cells, which give rise to the thymic epithelial cells instructing ...

Find out what you need to know about your thymus gland and its function. Learn the signs of a problem and how to protect this gland.

Scientists have been building thymus organoids for years using animal models. They have even grown and transplanted whole thymus glands in mice. Yet, no one has developed some from human cells ...

The epithelial cells, known as TECs (thymic epithelial cells), are further classified into cTECs (cortical TECs) and mTECs (medulla TECs). Thymic organogenesis is governed by the highly potent ...

Until now, scientists believed the thymus didn’t contain "true" epithelial stem cells. However, new findings show the presence of self-renewing stem cells, which give rise to the thymic epithelial ...

Medullary thymic epithelial cells (mTECs) allow the thymus to ensure that the body’s T cells are able to distinguish between potentially harmful foreign antigens and those that are produced by ...

A new preclinical model for thymic cancer developed by Weill Cornell Medicine investigators has revealed insights into how a common mutation found in thymic epithelial tumors sparks their ...