Following T cell commitment, developing T cells undergo multiple selection checkpoints by engaging with the extracellular matrix, and interacting with thymic epithelial cells (TECs) and other immune ...

Entering the thymus, precursor lymphocytes interact with the thymus stromal compartment mainly built of epithelial cells, and from the enormous variety of produced lymphocytes, only the specific ones ...

IgM is the first antibody to be produced in a humoral immune response and plays an important role in the primary stages of immunity. Here we describe a mouse Fc receptor, designated Fcα/μR, and ...

According to GlobalData, Phase II drugs for Thymoma (Thymic Epithelial Tumor) does not have sufficient historical ... of advanced stage metastatic malignant melanoma (US) and non-small cell lung ...

Amgen (NASDAQ:AMGN) today announced financial results for the fourth quarter and full year of 2024 versus comparable periods in 2023.

A team of international researchers led by scientists at City of Hope have demonstrated a way to boost thymic function after ...

The team’s study results, published today in the journal Immunity, outline their discovery of a specific type of regulatory T cell that can home back into the thymus and repair the organ when it's ...

There is potential for Tregs and amphiregulin to be used in patients receiving cancer therapies to ameliorate immune function.

A team of international researchers led by scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States, with its National Medical ...