Annual Reports in Medicinal Chemistry. Vol 47. Academic Press; 2012:367-378. 2. Edmondson R, et al. Three-dimensional cell culture systems and their applications in drug discovery and cell-based ...

In the end, they developed a culture system called Cultrex along with the kits for collecting and proliferating cells on three-dimensional matrices. “We are trying to integrate the matrix into ...

Cell culture is a fundamental technique in biotechnology and ... 3D cell cultures involve growing cells in a three-dimensional matrix or scaffold, allowing them to form more complex and ...

The way DNA folds inside the nucleus of brain cells may hold the key to understanding a devastating form of brain cancer called glioblastoma, suggests a new preclinical study. The findings offer a new ...

The way DNA folds inside the nucleus of brain cells may hold the key to understanding a devastating form of brain cancer ...

Two-dimensional cultures also neglect the role that the extracellular matrix plays in informing a cell's decisions, as well as in providing a physical space in which to form 3-D structures. "Most ...

Magnetism offers extremely promising perspectives in biology, particularly in mechanobiology and for various biomedical ...

Optimizing cell culture models to mimic the TME is vital to understanding ... However, they fail to replicate the complexity of three-dimensional (3D) tissue architecture and TME. Cells in monolayers ...

such as growth-factor proteins added to the culture medium, they can start to multiply and migrate, and even to show some degree of self-organization, resulting in three-dimensional cell–matrix ...

In the developing brain, neurons must navigate through complex and often crowded tissue to reach their final ...