News

Atom-swapping method successfully applied to complex organic structures—new possibilities for drug design
Skeletal editing is a modern approach to chemical synthesis. By making precise alterations at the atomic level, researchers ...
Redox-switchable dyes offer tunable fluorescence for advanced bioimaging and optical applications
Fluorescent molecules that absorb and emit light in the near-infrared (NIR) and short-wave infrared (SWIR) regions have ...
Discovering new ways to recharge T-cells fighting cancer
A pair of recent studies from the laboratory of Bin Zhang, MD, Ph.D., the Johanna Dobe Professor of Cancer Immunology, have ...
IEEE2d
Optimal Sizing of a Vanadium Redox Battery System for Microgrid Systems
Abstract: The vanadium redox battery (VRB) has proven to be a reliable and highly efficient energy storage system (ESS) for microgrid applications. However, one challenge in designing a microgrid ...
PNAS18d
Mechanism and application of thiol–disulfide redox biosensors with a fluorescence-lifetime readout
We thank J. Davis for letting us use his fluorometer, R. Padua for structural advice, D. Sabatini for advice on the manuscript, and E. Friedenthal; A. Longanathan; T. Clark; and M. Karkoski for ...
IEEE23d
Development of a Cooling System for Vanadium Redox Flow Batteries
Abstract: This study focuses on designing and optimizing a plate heat exchanger for a vanadium redox flow battery's cooling and thermal stabilization system. Thermal and hydraulic calculations were ...
C&EN24d
Targeting Apicomplexan Parasites: Structural and Functional Characterization of Cryptosporidium Thioredoxin Reductase as a Novel Drug Target
Department of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila 67100, Italy Department of Science, Technology and Society, University School for Advanced Studies of Pavia, ...
C&EN27d
Comparative Study of Click Handle Stability in Common Ligation Conditions
Click handles that were previously identified to show instability under different conditions were selected (BCN, unstable to GSH over 24 h and tetrazine-Me, unstable to pH 10, TCEP and CuAAC cocktail ...