Whilst the ultimate outcome of the lytic cycle is production of new phage progeny and death of the host bacterial cell, this is a multistep process involving precise coordination of gene transcription ...

Bacteriophages are viruses that infect bacteria. Some phages follow a lytic life cycle where they inject their DNA into the host cell and hijack its mechanisms to reproduce. When the number of ...

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Herpesvirus-encoded microRNAs (v-miRNAs) play a crucial role in modulating host cellular processes to promote viral persistence, immune evasion, and pathogenesis. These v-miRNAs function by targeting ...

In spite of recent advances in the management of multiple myeloma, cure has been elusive, with efforts to improve long-term outcomes thwarted by repeated cycles of relapse and remission. This is ...

We engaged with the FDA in a productive mid cycle review meeting this past week ... and destroy tumor cells without compromising its lytic activity. It's designed to enter a broad spectrum ...

HSV-1/2 pUL14 is predicted to be a 219 amino acid protein with a molecular mass of 23 kDa. Figure 3. The lytic replication cycle of herpesviruses. (1) Entry into the cell (steps ①, ②), (2) transfer of ...

Certain necrotrophs may also live as saprophytes during their life cycle, while others may live only as obligate ... relating to the identification of Fusarium oxysporum. Keywords: toxins, lytic ...

Being a cycle breaker can feel like both a burden and a gift. Here are some signs you may be breaking the cycle of trauma.