(4) Multiple factors, such as intraocular pressure (IOP), oxidative stress, mitochondrial malfunction ... an essential component in the pathogenesis of glaucoma. Minocycline, a tetracycline derivative ...

Everything the brain does—from storing memories to interpreting sights to regulating emotions—requires energy, all produced by cellular organelles called mitochondria. However, surprisingly ...

Mapping the density, molecular features and energy-transformation capacity of cell organelles called mitochondria in the brain reveals region- and cell-type-specific variability that tracks with ...

Get Instant Summarized Text (Gist) High-resolution cryo-electron tomography has revealed the intricate architecture of mitochondrial supercomplexes, which are crucial for cellular energy ...

Acute liver failure (ALF) in children differs from that observed in adults in both the etiologic spectrum and the clinical picture. Children, particularly very young ones, do not demonstrate ...

The flux of protons from respiratory supercomplexes (blue) to ATP producing complexes (pink) powers the regeneration of ATP in mitochondria. Credit: Biozentrum ...

Mutations in the mitochondrial genome (mtDNA) often lead to clinical pathologies. Mitochondrially-targeted zinc finger nucleases (mtZFNs) have been successful in reducing the levels of ...

aThe Cardiac Exercise Research Group at the Faculty of Medicine and Health Sciences, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. This longitudinal single-cell transcriptome ...

Department of Life Sciences and Systems Biology, University of Torino, Torino 10123, Italy School of Neurobiology, Biochemistry and Biophysics, The George S. Wise Faculty of Life Sciences, Tel Aviv ...

The content on this site is intended for science and health care professionals. We use cookies to help provide and enhance our service and tailor content and ads. To update your cookie settings, ...