Testicular cancer is when unusual cells grow out of control in the tissue of one or both of your testicles. Also called testes, these are the two oval-shaped organs that hang from the base of a ...

Ipsen secures exclusive global rights to develop, manufacture and commercialize BMX-502, a pre-clinical novel T cell engager (TCE ... development of disruptive immuno-therapies for the treatment ...

The sperm epigenome is shaped in a compartment protected by the blood-testes barrier (BTB ... Amherst. Fig. S1. Immunohistochemistry analysis of the efficiency of Rictor and Raptor KO in Sertoli cells ...

Colorectal tumor infiltration by a variety of different immune cell types correlates with better prognosis ... CT, core of the tumor; IHC, immunohistochemistry; IM, invasive margin. Tissue samples ...

The research builds upon previous findings from Drosophila studies, aiming to elucidate the impact of Fat1 knockdown on Sertoli cell function and the integrity of the blood-testis barrier (BTB) in ...

the granulosa cells rapidly turn into Sertoli-like cells, and the gonads come to resemble testes. Sertoli cells are the testicular cells that usually support sperm formation in XY males ...

The artificial testicles were cultured from immature testicular cells sampled from neonatal mice. The research team realized the procedure was a success when they identified tubule-like structures and ...

The mice used in the study had been genetically engineered to allow the researchers to track the presence and state of Sertoli cells, which are essential for testis formation and sperm production ...

There are different types of testicular cancer. The type of cancer depends on which type of cell it started in. Knowing the type helps your doctor decide which treatment you need. Most testicular ...

An impaired Sertoli cell function could be attributed to an inadequate number of germ cells. A lower serum AMH manifests as threefold lower sperm quantity and smaller testis size in men.

"The testis is not quiescent in childhood and is sensitive to the hormone insulin. Obesity and metabolic impairment actually can have an effect and negative impact on Sertoli cell proliferation ...