A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

In a new move, researchers have shown that protein design software can incorporate motion into its outputs. The resulting ...

A joint study conducted by the Henan University of Technology (Zhengzhou, China) and the Food Laboratory of Zhongyuan (Henan ...

Our cells rely on microscopic highways and specialized protein vehicles to move everything—from positioning organelles to carting protein instructions to disposing of cellular garbage. These highways ...

This manuscript introduces a useful protein-stability-based fitness model for simulating protein evolution and unifying non-neutral models of molecular evolution with phylogenetic models. The model is ...

RNAs must fold into unique three-dimensional structures to function in the cell, but how each polynucleotide finds its native structure is not understood. To investigate whether the stability of the ...

RevolKa Ltd. (RevolKa), a venture-backed biotech company providing a cutting-edge AI-driven protein engineering technology ...

These dityrosine crosslinked proteins may provide a structural matrix for assembly of the oocyst wall and contribute to its resilience. The oocyst wall of coccidian parasites is a robust structure ...

Protein folding is the process by which proteins achieve their mature functional (native) tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often ...

An enzyme as key to protein quality Date: May 9, 2025 Source: University of Würzburg Summary: In neurodegenerative diseases such as Alzheimer's or Parkinson's, proteins accumulate in the body's ...

Data from biochemical analyses, proteomics and functional genomics have improved our understanding of the structure, function and regulation of the proteins located in the nucleoids and contributed ...

First we describe the reduced parameter protein model we use to interpret BioSAXS data ... model are constructed to produce theoretical scattering curves for this tertiary structure model.