The continuous, solid-phase system achieved a refolding yield of approximately 100% by gradually pumping lysozyme through the ...

This manuscript introduces a useful protein-stability-based fitness model for simulating protein evolution and unifying non-neutral models of molecular evolution with phylogenetic models. The model is ...

Researchers from Ruhr University Bochum, Germany, have developed a new method that allows them to visualize the contribution ...

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized ...

Protein folding is the process by which proteins achieve their mature functional (native) tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often ...

Dublin, May 07, 2025 (GLOBE NEWSWIRE) -- The "3D Protein Structure Analysis Market - A Global and Regional Analysis: Focus on Product, End User, and Region - Analysis and Forecast, 2025-2035" report ...

Researchers have captured a time-resolved video of a protein interaction essential to healthy brain development.

which predicts the 3D structure of a protein based on its amino acid sequence, by layering in a foundational dataset (BaseGraph) that considers how proteins behave in the ‘real world’, i.e ...

First discovered in 2001, the protein PINK1 has been directly linked to Parkinson ... researchers from the Walter and Eliza Hall Institute of Medical Research (WEHI) have determined the structure of ...

The latest version of Google DeepMind and Isomorphic Labs’ AlphaFold model can predict the structure and relationships not only of proteins ... to apply it to real-world drug design challenges ...

To solve this problem, we propose a graph neural network (GNNGO3D) that combines the three-dimensional structure and functional hierarchy learning. GNNGO3D simultaneously uses three kinds of ...