The broad-spectrum antibiotic piperacillin-tazobactam used as perioperative prophylaxis significantly reduced surgical site infection (SSI) in patients undergoing open pancreatoduodenectomy (PD, or ...

PHILADELPHIA, PA—Ceftolozane/tazobactam provides an empiric treatment option for infections caused by extended-spectrum β-lactamase (ESBL)-producing ...

Piperacillin 2g, tazobactam 0.25g (2.25g vial); or piperacillin 3g, tazobactam 0.375g (3.375g vial); or piperacillin 4g, tazobactam 0.5g (4.5g vial); lyophilized pwd for IV inj after ...

The FDA approved the combination of cefepime and enmetazobactam (Exblifep) for the treatment of adult patients with complicated urinary tract infections, including pyelonephritis, caused by ...

The addition of tazobactam broadens coverage to include most Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli (E. coli), Klebsiella pneumoniae, and other Enterobacteriaceae.

“These findings suggest that broad-spectrum antibiotics with anti-anaerobic activity, such as piperacillin-tazobactam, may cause harm in patients without a clear indication,” the authors wrote.

Intra‑abdominal infections include a wide spectrum of conditions, from uncomplicated appendicitis to faecal peritonitis. In complicated intra‑abdominal infections, the infection progresses from a ...

Treatment with the commonly used antibiotic piperacillin/tazobactam was associated with a 5 percent increase in 90-day mortality, more days on a ventilator, and more ...

A phase 2 randomized clinical trial found that ceftolozane/tazobactam was a safe and effective option for the treatment of children with complicated UTIs, researchers ...

In a randomised controlled trial (RCT) in adults with complicated urinary tract infections or acute pyelonephritis (ASPECT-cUTI), an intravenous (IV) infusion of ...

Exblifep is a combination of cefepime, a fourth-generation cephalosporin, and enmetazobactam, a novel extended-spectrum beta-lactamase ... effective as piperacillin-tazobactam in the treatment ...