Researchers at the Max Planck Institute for Evolutionary Anthropology have addressed a longstanding challenge in CRISPR ...

Aided by RNA origami, the Heidelberg synthetic biologist and her team succeeded in creating an essential structural component of synthetic cells -- an artificial cytoskeleton.

Additionally, by employing single guide RNA (sgRNA) as the recognition RNA motif ... and expanding the application of synthetic biological tools.

The team has demonstrated efficient enrichment of synthetic RNA molecules and small molecules in the kidney, and that platform may be useful for treating conditions like kidney fibrosis.

In this article, we’ll briefly discuss several RNA-seq workflows, how they differ, and the advantages and drawbacks of each. Regardless of the method you choose, every RNA-seq project begins with ...

Dai Jianwu and Zhao Yannan from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences employed a combination of lineage tracing and single-cell RNA sequencing ...

As part of these so-called CRISPR-Cas systems, a CRISPR ribonucleic acid (crRNA), which serves as a "guide RNA," recognizes ... head of the RNA Synthetic Biology department at the Helmholtz ...

14 This technology involves short, synthetic single-stranded oligonucleotides that are complementary to the siRNA guide (antisense) strand loaded in the RNA-induced silencing complex and that target ...

Endogenous RNA is central to protein control and, ultimately, cellular function. Synthetic RNA is an important ... Base editing techniques that require only single-strand DNA breaks and offer ...

Named Sc-SPORT for Single Cell Structure Probing Of RNA Transcripts, this new approach is able to identify biomarkers crucial for human development and disease, based on shape rather than sequence ...

Laboratory for Genome Engineering and Synthetic Biology ... activities that enable nonspecific cleavage of single-stranded DNA (ssDNA) and RNA (ssRNA). When Cas12 or Cas13 are programmed with a guide ...