This study revealed that, by binding to lipoproteins, cholesterol-conjugated heteroduplex oligonucleotides (Chol-HDOs) can remain in the bloodstream for longer and reach brain tissue much more ...

Evercore ISI highlighted strong market feedback for competitors in the PMO (phosphorodiamidate morpholino oligomer) space, acknowledging that while FDA uncertainties might benefit Sarepta ...

Net product revenues for the first quarter 2025 totaled $611.5 million, a 70% increase over the same quarter of the prior year ELEVIDYS net product revenue for the first quarter totaled $375.0 ...

DYNE-251 consists of a phosphorodiamidate morpholino oligomer (PMO) conjugated to a fragment antibody (Fab) that binds to the transferrin receptor 1 (TfR1), which is highly expressed on muscle.

The Chromatographic Society and RSC Separation Science Group are pleased to announce, Analytical Horizons in Oligonucleotide Separation Science. The Spring Symposium will be held on Wednesday 7th May ...

DYNE-251 consists of a phosphorodiamidate morpholino oligomer (PMO) conjugated to a fragment antibody (Fab) that binds to the transferrin receptor 1 (TfR1), which is highly expressed on muscle. It is ...

According to the company, the therapy comprises a phosphorodiamidate morpholino oligomer, which is conjugated to a fragment antibody that attaches to the transferrin receptor 1, facilitating the ...