News

Simultaneously targeting lysosomal enzyme and KRAS-MAPK pathway eradicates pancreatic tumors in preclinical models
Pancreatic cancer is a leading cause of cancer-related death, with a five-year survival rate of 13%. The high mortality is ...
eLife3d
Identification of the Regulatory Elements and Protein Substrates of Lysine Acetoacetylation
This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...
C&EN23d
The Missing Enzymes: A Call to Update Pharmacological Profiling Practices for Better Drug Safety Assessment
Department of Foundational Medical Studies, William Beaumont School of Medicine, Oakland University, Rochester, Michigan 48309, United States *Address: William Beaumont School of Medicine, Oakland ...
C&EN25d
Biocatalytic Preparation of High-Purity DHA-Enriched Partial Glycerides through Semirational Design and Modification of Lipase Lip1897
State Key Laboratory of Marine Food Processing and Safety Control, College of Food Science and Engineering, Ocean University of China, Qingdao 266404, P. R. China Laboratory for Marine Drugs and ...