This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

CDK9, a core component of positive transcription elongation factor b (p-TEFb) playing a crucial role in RNA polymerase II transcription (RNAP ... we performed a rational design and structure-based ...

This study reports two cryo-EM structures of the Nipah virus (NiV) polymerase L-P complex in its full-length and truncated ...

Failure of a gene-reading quality-control mechanism called Integrator leaves cells littered with abnormal RNA strands that ...

Despite being the backbone of modern transcriptomics, traditional short-read RNA sequencing often fails to capture full-length RNA molecules and complex ... full sequence structure of RNA to ...

Unlocking the Full Picture of RNA Despite being the backbone of modern transcriptomics, traditional short-read RNA sequencing often fails to capture full-length RNA molecules and complex ...

This study finds these bacteria as the first example of an organism using ADP-ribose modification of DNA as a mechanism for regulating gene transcription ... inability to form the open complex or an ...

Water present at the interface of a protein–RNA complex plays a critical role in guiding its structure, stability, and function. Therefore, studying the microscopic properties of interfacial water is ...

RIT’s biomedical sciences BS consists of life sciences core courses combined with flexible electives to customize your degree for medical school or full-time employment. Comprehensive Course Work: A ...