This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

This study reports two cryo-EM structures of the Nipah virus (NiV) polymerase L-P complex in its full-length and truncated ...

Failure of a gene-reading quality-control mechanism called Integrator leaves cells littered with abnormal RNA strands that ...

This study finds these bacteria as the first example of an organism using ADP-ribose modification of DNA as a mechanism for regulating gene transcription ... inability to form the open complex or an ...