Here we report the structure of an entire HIV-1 genome at single nucleotide resolution using SHAPE, a high-throughput RNA analysis technology. The genome encodes protein structure at two levels.

"Characterizing the structure of HIV RT was a critical turning point in ... Repetitive elements in the genome such as HERV-K are frequently overexpressed in cancer and elicit biological viral ...

The role of the structure and organization of the host genome in HIV-1 infection is not well understood. Using a cell culture model based on brain immune microglia cells, an international research ...

Shape of things to come: Structure of HIV coat could lead to new drugs. ScienceDaily . Retrieved May 22, 2025 from www.sciencedaily.com / releases / 2009 / 11 / 091112121559.htm ...

A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure ... (HIV) is a retrovirus which has its RNA genome ...

A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues ...

The enzyme RT of HIV-1 is responsible for copying the viral single-stranded RNA genome to double-stranded DNA (dsDNA) in the cytoplasm of infected cells. This 117-kDa heterodimeric (p66 and p51 ...

so knowing its structure in detail could lead us to new drugs that can treat or prevent the infection. "The capsid has to remain intact to protect the HIV genome and get it into the human cell ...

Knowledge of Env structure and dynamics has nevertheless played an important role in HIV-1 vaccine immunogen design, the team, continued. But, while parts of the envelope are constantly moving to ...

Chances are you've seen an illustration of DNA's double-helix structure and even pictures of the chromosomes that make up the human genome. But where and how does the famous double helix fit into ...