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Several mRNA vaccine trials found a debilitating side effect, and now the Trump administration is cutting funding for more ...
The discovery of recombinant DNA proved that biology, not chemistry alone, could create new medicines like life-saving ...
A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host ...
A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues ...
The role of the structure and organization of the host genome in HIV-1 infection is not well understood. Using a cell culture model based on brain immune microglia cells, an international research ...
"Characterizing the structure of HIV RT was a critical turning point in ... Repetitive elements in the genome such as HERV-K are frequently overexpressed in cancer and elicit biological viral ...
Previous attempts at making HIV vaccines elicit an important ... trimer—proteins that mimic the structure of the spike target for antibodies—into DNA that was delivered into mice.
Deborah Fuller is co-founder of Orlance, Inc, a biotechnology company developing a needle free technology to deliver RNA and DNA vaccines ... diseases – like HIV, hepatitis B and herpes ...
A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure ... (HIV) is a retrovirus which has its RNA genome ...
Left: Structure of the Human Immunodeficiency Virus (HIV). Note the envelope protein that protects the virus against immunological detection and the small genome consisting of two short strands of ...
The HIV capsid has tiny pores in it ... making up the capsid held their lattice-like structure stable throughout reverse transcription. As the DNA strands grew larger, their ends sometimes ...
“The DNA structure is like a pegboard where the antigens ... They attached an engineered HIV antigen related to the gp120 protein to the scaffold at a variety of distances and densities.
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