We don't always understand our emotions, but we couldn't lead normal lives without them. They steer us through life, guiding the decisions we make and the actions we take. But if they're inappropriate ...

† Department of Applied Molecular Bioscience, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan § Department of Advanced Bioscience, Faculty of Agriculture, Kinki ...

Autoantibodies against GFAP may represent a new and early serum marker of high diabetes risk in NOD mice. B-and T-cell autoimmunity to pSC constituents in NOD females. a, NOD mice, but not C57BL/6 ...

The measure of stimulated salivary flow was performed throughout the study and the other experiments were performed at sacrifice, between ages 18 and 20 weeks, in mice that had not become diabetic. As ...

Most approaches to developing new treatments for diabetes are based on traditional laboratory animals such as mice because they are easy to reproduce and study in a lab. But outside the lab ...

CHICAGO, Aug. 1, 2022 /PRNewswire/ -- Cour Pharmaceuticals a clinical stage biotechnology company developing novel immune-modifying nanoparticles (COUR NanoParticles or CNPs) designed to reprogram the ...

Autoimmune diabetes arises spontaneously in Non-Obese Diabetic (NOD) mice, and the pathophysiology of this disease shares many similarities with human type 1 diabetes. Since its generation in 1980, ...

T-cell responses to insulin and its precursor proinsulin are central to islet autoimmunity in humans and non-obese diabetic (NOD) mice that spontaneously develop autoimmune diabetes. Mice have two ...

Next, the scientists turned their attention to non-obese diabetic (NOD) mice. These animals spontaneously develop diabetes because their overly aggressive immune systems readily provoke beta (insulin) ...

About 60% of control mice showed spontaneous diabetes by 24 weeks of age, while no OCA-B-deficient animals became diabetic, the team reported. RELATED: How a cocktail of existing drugs could ...