In vitro generation of DCs from mouse and human tissues such as bone marrow and peripheral blood monocytes, has been widely used to study their immunological functions. In chicken, DCs have mainly ...
In this article, we propose a novel pathogenic mechanism whereby CD14+monocyte-derived oxidised mtDNA induces IFN stimulatory gene (ISG) expression in the rare childhood autoimmune disease JDM. We ...
Chemokines are a family of chemotactic cytokines that play indispensable roles in vascular ... We further validated that the monocyte-derived CXCL12a was essential for guiding this process via the ...
Accordingly, even under steady-state conditions, BM-derived cells contribute to the ... differentially imparted across recruited trained monocytes from the BM and diverse MP populations within the ...
This made it possible to replace the mice’s own macrophages with fluorescently labelled cells derived from monocytes. Fluorescent monocytes were introduced into the bloodstream and arrived in the ...
Within the tissues they are activated for phagocytosis as well as secretion of inflammatory cytokines, thereby playing major ... hematopoiesis has started (E10.5 in mice), fetal liver-derived ...
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