A sponge-like implant in mice helped guide a treatment that slowed or stopped a degenerative condition similar to multiple sclerosis in humans. It also gave University of Michigan researchers a first ...

Spinal cord injury (SCI) is characterized by the temporary or permanent loss of motion or sensation function caused by damage to the spinal cord. Among the mechanisms behind SCI, neuroinflammation is ...

Three patients with spinal muscular atrophy had improved muscle strength and could walk farther after a month of daily spinal ...

An experimental treatment that stimulates the spinal cord may help people with a paralyzing ... HAMILTON: But Mentis showed that in mice with SMA, the disease also disrupts connections between ...

Daily electrical stimulation of certain nerves in the spinal cord appeared to help three people ... But Mentis showed that in mice with SMA, muscle weakness appeared before motor neurons started ...

Neuropathologically, these mice exhibit widespread tau pathology, affecting the cerebral cortex, hippocampus, brain stem, and spinal cord. In the spinal cord, tau pathology leads to a dramatic loss of ...

We analyzed the effect of chronic (10 weeks) food diet containing GW2580 (a CSF1R inhibitor) in mice that underwent lateral spinal cord hemisection (HS) at vertebral thoracic level 9. Treatment ...

Thoracic spinal cord contusion injuries were performed on 8–12 weeks-old female mice. To expose the spinal cord, a laminectomy was performed on the T8–T11 vertebrae. The contusion injury was induced ...