Researchers found that TEX38 and ZDHHC19 co-localize on the plasma membrane of spermatids and mediate S-palmitoylation of ARRDC5, a crucial protein for spermatogenesis. Disrupting either TEX38 or ...

“While some genes that are essential for spermiogenesis have been identified, there is much that remains unknown about the molecular mechanisms of this intricate process.” To explore factors ...

"While some genes that are essential for spermiogenesis have been identified, there is much that remains unknown about the molecular mechanisms of this intricate process." To explore factors that may ...

During spermiogenesis, these spermatids undergo significant morphological changes to mature into genetically and epigenetically competent sperm. Genomic and epigenetic alterations in germ cells and ...

In contrast, XAP5L negatively regulates the expression of ciliary genes via repressing these ciliary transcription factors during the spermiogenesis stage. Our results provide new insights into the ...

The linker histone H1 binds to the nucleosome core particle at the site where DNA enters and exits, and facilitates folding of the nucleosomes into a higher-order chromatin structure in eukaryotes.