The efficiency of nuclear transfer remains extremely low (<2%) and high rates of perinatal mortality are observed, particularly when adult somatic cells are used as donor karyoplasts. This ...

tmd.ac.jp Progressive accumulation of specific misfolded protein is a defining feature of amyotrophic lateral sclerosis ... cells; this is similar to the behaviour of the characteristic pathogenic ...

Explore Brainstorm Cell Therapeutics' Q1 2025 earnings call highlights, including FDA clearance for their ALS Phase 3b trial, funding efforts, ...

The researchers investigated why some nerve cells in fruit fly brains are resistant to disease processes that cause frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS ...

New technique for cell or drug delivery, localization of bioelectric materials, and wound healing uses ultrasound to activate printing within the body. Imagine if doctors could precisely print ...

Researchers found that inhibiting GSK-3 led to less defects in the axonal transport process and less neuronal cell death, while inhibiting ERK1 led to more transport problems and more cell death.

The team tested a variety of ALS drugs on this broad collection of cells, with the goal of reducing or preventing abnormal protein accumulation outside the cell nucleus. Specifically, drugs were ...

For decades, scientists and surgeons around the world have been trying to solve the organ donor crisis. The answer could be rolling in the mud. At a farm and lab in the Midwest, biotechnology ...