While Berberine is touted as a natural alternative to Ozempic, its AMPK modulation differs from GLP-1 pathways, highlighting the need for cautious use.

Leveraging whole slide embedding from pretrained foundation models (FMs) improves nonmelanoma skin cancer (NMSC) diagnosis, ...

Cold' tumors are resistant to common immunotherapies. Researchers have uncovered a master regulator that can be manipulated to prevent tumor growth in mice.

Millions of people compulsively pick their skin or pull their hair. Social media is helping some of them to recover.

The skin is the largest organ in the human body. It makes up about 15% of our body weight and protects us from pathogens, dehydration and temperature extremes. Skin diseases are therefore more than ...

Center for Drug Discovery, Research Triangle Institute, Research Triangle Park, North Carolina 27713, United States ...

“This is a biomimetic skin phantom. It consists of two layers. The top part, the black part, is made of a polymer that's called PDMS,” explained Goyal. The phantom is a model that mimics the ...

Our findings suggest that blocking HPGDS or the two downstream receptors may be a new potential strategy for improving treatment options for melanoma patients and perhaps others facing similar ...

This study identifies a novel therapeutic approach by selective targeting formyl-peptide receptor 2 (FPR2) to mitigate these secondary organ injuries. A novel mouse model of arthritis with high ...

using an animal model of disease. They found that topical application directly to the skin every day for seven days in an emollient cream resulted in a clear reduction in disease compared to ...